Substrate specificity of prostate-specific membrane antigen

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Substrate specificity of prostate-specific membrane antigen.

A series of putative dipeptide substrates of prostate-specific membrane antigen (PSMA) was prepared that explored alpha- and beta/gamma-linked acidic residues at the P1 position and various chromophores at the P2 position, while keeping the P1' residue constant as L-Glu. Four chromophores were examined, including 4-phenylazobenzoyl, 1-pyrenebutyryl, 9-anthracenylcarboxyl-gamma-aminobutyryl, and...

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ژورنال

عنوان ژورنال: Bioorganic & Medicinal Chemistry

سال: 2007

ISSN: 0968-0896

DOI: 10.1016/j.bmc.2007.08.006